You can measure the effects of audiophile cables- the trick is to measure the system spectral bandwidth in the room rather than the cable itself. On the bench it seems harder to quantify the effects of one cable to another like you can measure in a functioning system, and the effects of a given cable will vary from system to system. A simple trick- make the cable in question longer and see if its easier to see its effects.
There are several points here:
1) Some cables deliberately add an R/C rolloff. Of course this is audible, but this is not doing what a cable should do, it's what an equalizer or tone control is for.
2)
You ***MUST*** test cables in-situ, or you have zero idea how they will interact with other equipment, like driving impedence, current sourcing, etc. While those should not be a problem, the word "should" is there for a reason.
3) As somebody pointed out, the phone company has worked on this a lot. If the tomfoolery about quantum effects, "grain rectification" and the like were true, cross-town telephony would have never worked, let alone cross-continent telephony. It does, ergo silly tomfoolery is tomfoolery.
Now, I have heard cables make a difference in several ways. The first was when somebody got one of the first audiophile speaker cables (that had mind-boggling capacitance), and connected them to a high-end amplifier. The "pop" as the output transistors died (the amp was not stable into such a huge capacitive load, please feel free to point fingers at whichever you like, I'm not going to even name the components) was quite audible as was the "dead silence" that resulted, followed by the sound of windows opening to let out the smell of burning resistor.
The second was in a lab, a very carefully set up lab that thanks to equipment design required some RCA single-ended connections. Ok, something sounds wrong. Hm. I did some measurements, and sure enough something was center-clipping. Removed cables, etc. No evidence. Put them back in, no center clipping. Examining some of the connectors (tin on gold bad) showed some corrosion, and removing and reinserting the connectors scraped through it. So MOVING the cable made a difference. The cables should never have been tin on gold (jacks) to begin with, and you may be confident that was resolved promptly, of course.
I wonder some days if that isn't the cause of "improvements" attributed to cables, and if reseating all cables would have a similar effect.
Connectors do matter, there is no real doubt, but all they have to do is get it right. RCA connectors, by their design, kind of suck, but it's hard to get around them.