After spending a few weeks with both the Shunyata Omega-X and the Synergistic Research Galileo Discovery USB cables, both in the $3K range, here's what I found:
Galileo Discovery (Gold module). -- a little laid back, easy listening in the best of senses, clear, articulate, tight, clean, smooth, balanced. It comes with the Gold and Master modules. So far I've found the Gold does everything a touch better.
Omega-X — Swings!, alive, expansive, clear, detailed, a little on the neutral side, in many ways an ideal sound
Both are clearly a-level-above cables. I hope to get another shot at the Omega-X to see if I can coax my system a smidgeon into the warm side with it. I had started to move there when I had to return it.