...I have seen a few articles around this topic. Unfortunately, I cannot find the image with various microscopic sections under various "pull speeds," temp, etc. I don't have a dog in this fight (she's on the chair at the moment).
"The effect of grain boundaries on the
strength and
electrical conductivity of annealed copper wires was studied. After annealing at 100 °C for 30 min, the copper wires retained a fiber-like structure. The increase in electrical conductivity is believed to stem from the decrease of
crystallographic defects introduced by drawing. Recrystallization occurred when the annealing temperature reached 150 °C. The formation of small recrystallized grains led to the introduction of additional grain boundaries perpendicular to the drawing direction, resulting in a slight decrease in electrical conductivity."
Volume 26, September–October 2023, Pages 1459-1468
I don't personally think it's a stretch that grain directionality makes a difference in sound, but it would likely be a part of a "system" containing many variables, and may be difficult to measure, other than with ears and one's brain. Not everyone hears everything.