Actually yes they do seem to do things a bit differently.
The Shunyata Typhon is just a noise suppression device. And it takes 4-5 days to settle down after it's been plugged into a circuit. But after a few days, it's effects are unmistakable. The background haze (that you don't even realize is there) is lessened allowing each musical note to possess a bit more energy. It does not change really any other parameters. But when you pull the plug...you're like...ugh...and plug it back in fast. It's my favorite Shuyata conditioning product.
The Shunyata DPC-6v2 is just to firewall off the back wave of digital noise from going back into the system. The best example here is my turnable motor controller. It's a digital signal processor, basically a small dedicated computer, has a wall wart type of power supply (which are known to be noisy too). With all the digital (Vivaldi etc) off, and unplugged, and JUST the motor controller into the DPC-6 v2 vs the wall where the preamps are...it was introducing a smearing effect to the vinyl playback. It was easy and quick to test. Just plug into the DPC6 listen then move to a outlet where the preamps where. Even if those outlets happened to be a Triton V2...it was still putting noise into that circuit which when removed...was for the better.
The Opus Isolator seems to be much broader is what its doing. Lower noise, better dynamics, better textures, more ease but more power in the music. It cleary makes the music more interesting to listen too in every area. I wish I know what what inside it ... it's about 15 pounds...so something is in there !