Direct-coupled tube preamps and amps have been around for ages but rarely commercialized, probably due to reliability issues. At least that was the problem with my direct-coupled tube preamp. The other problem was that I cleverly used a fully differential design, and the resulting sound (while measurably better than most other tube gear) was deemed "too SS-like".
Class D amplifiers use a non-linear (extremely nonlinear) output stage, require fairly high (for audio) switching rates, and a reactive filter at the output, all of which makes closing the feedback loop around the circuit very challenging. Phase shift is nonlinear and getting a stable design is tough, particularly if the load is varying (loudspeaker, anyone?) The combination of switching output stage and output filter makes them pretty load-sensitive. The output devices are subject to switching transients, exacerbated by the output filter, so need special protection. The output devices' timing (of their switching) is critical to avoid blowing them up. Finally, the ideal response depends upon a perfect power supply. An analogy is to think of switching between "0" and "1" but in this case the "0" and "1" levels are set by the power supply rails since that's what you are switching the output to and from. If the supply voltage "wiggles", it is translated to the output. Now consider you are switching gobs of current very fast, leading to large current spikes, and envision how hard it is to keep those power rails from wiggling. There's a lot more devil in a lot more details but those are the big ones I recall off-hand. It has been a while since I did a class D design.
Done well, they are great, but by and large I think they have a bit to go.